Abstract of Computational Science Seminar

Bioinformatics: Deciphering the Rosetta Stone of Biology Prof. Shankar Subramaniam

Biology is going through a period of fundamental change. The complete genome sequence for an increasing number of organisms is becoming available. Currently, the full DNA sequence for several unicellular organisms are at hand and it is expected that the full DNA sequences will become available for well known multi-cellular organisms within a few years. The most pressing problem in the post-genome sequencing era will be to understand the integrated functions of thousands of genes. This forms the core of the new central dogma, shown below. This talk will highlight computational approaches to assigning structure and function to gene products and the creation of a web-based infrastructure for biological databases, interfaces and analysis tools.