Results from the development and teaching of a senior-level undergraduate multidisciplinary course in high performance computing are presented. Having been taught four times, there are several "Lesson Learned" presented in this paper. Help from the technical staff at the San Diego Supercomputer Center and support from the National Science Foundation has been instrumental in the evolution of this course. The work of faculty at other universities has influenced the author's courses and is gratefully acknowledged. A subsequent sophomore level course was developed at SDSU and has become part of a voluntary, cooperative program, Undergraduate Computational Science and Engineering.